Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shoushtar Faculty of Medical Sciences

Vitamin D, testosterone and depression in middle-aged and elderly men: a systematic review

(2021) Vitamin D, testosterone and depression in middle-aged and elderly men: a systematic review. Critical Reviews in Food Science and Nutrition. p. 12. ISSN 1040-8398

Full text not available from this repository.

Official URL: <Go to ISI>://WOS:000730101100001

Abstract

Depression is one of the common psychiatric disorders during elderly. This systematic review aims to present the relationship between vitamin D deficiency, depression and testosterone serum concentration in the middle-aged and elderly men. We performed a comprehensive search in the Google Scholar, PubMed, ProQuest, Web of Science, Cochrane, Science Direct, and Scopus databases to collect any relevant published studies. The data of the articles that had been investigated the relationship between depression and 25-hydroxy vitamin D (25OHD) serum concentration (nine studies), or testosterone and 25OHD (six studies), as the primary outcomes, were included in our review. The results of the cohort and cross-sectional studies have shown that vitamin-D deficiency is associated with the incidence of depression in older men. In addition, documents have reported the positive association between vitamin D and testosterone, and previous studies have shown that testosterone can involve in the mood. We have proposed scientific mechanisms that have shown vitamin D may also play a protective role in depression through its effect on the testosterone. Therefore, it is a low risk and safe recommendation for the middle-aged and elderly men to use the vitamin D supplement or exposure to the sunlight to prevent depression.

Item Type: Article
Keywords: Depressive mood 25-hydroxy vitamin D andropause men aging systematic review SERUM 25-HYDROXYVITAMIN D OLDER MEN ANDROGEN DEFICIENCY HEALTHY-MEN AGING MEN ASSOCIATION MOOD HYPOGONADISM SYMPTOMS HORMONES
Divisions: Shoushtar Faculty of Medical Sciences > Faculty of Medicine > Department of Basic Science > Department of Nutrition
Page Range: p. 12
Journal or Publication Title: Critical Reviews in Food Science and Nutrition
Journal Index: ISI
Identification Number: https://doi.org/10.1080/10408398.2021.2015284
ISSN: 1040-8398
Depositing User: خانم نجمه نوارباف
URI: http://eprints.shoushtarums.ac.ir/id/eprint/399

Actions (login required)

View Item View Item